The Journal of Targeted Oncology Research (JTOR) is an international, open-access, peer-reviewed scholarly journal dedicated to publishing high-quality research that advances the understanding, diagnosis, and treatment of cancer through targeted and precision-based approaches. The journal serves as a global platform for scientists, clinicians, and healthcare professionals engaged in innovative oncology research, with a strong emphasis on translating scientific discoveries into effective clinical applications.

Aims of the Journal

To Advance Cancer Biology Research
Promote fundamental and applied research that enhances understanding of cancer initiation, progression, metastasis, and molecular signaling pathways.

To Support Innovation in Targeted Therapies
Highlight the discovery, development, and optimization of targeted anticancer therapies, including small-molecule inhibitors, monoclonal antibodies, antibody–drug conjugates, immunotherapies, and gene- and cell-based treatments.

To Bridge Bench-to-Bedside Research
Encourage translational oncology studies that integrate laboratory findings with clinical practice to improve patient outcomes.

To Promote Precision and Personalized Oncology
Advance research focused on individualized cancer treatment strategies based on genetic, molecular, and clinical patient profiles.

To Foster Interdisciplinary Collaboration
Facilitate collaboration among oncology, molecular biology, pharmacology, genetics, immunology, bioinformatics, and biomedical engineering disciplines.

To Disseminate Evidence-Based Oncology Practices
Publish clinically relevant research that supports best practices and improves standards of cancer care globally.

To Encourage Global Oncology Research
Provide a platform for cancer research addressing regional and global cancer burdens, disparities in care, and emerging challenges in oncology.

Scope of the Journal

JTOR publishes original research articles, review articles, short communications, case reports, and clinical studies covering a broad range of topics, including but not limited to:

Cancer Biomarkers and Diagnostics
Identification and validation of molecular, genetic, and imaging biomarkers for early detection, prognosis, and therapeutic response prediction.

Cancer Genomics, Epigenetics, and Proteomics
Studies exploring genomic alterations, epigenetic regulation, proteomic profiling, and their role in tumor behavior and therapy selection.

Tumor Microenvironment and Immuno-Oncology
Research on immune modulation, tumor–host interactions, immune checkpoint inhibitors, cancer vaccines, and adoptive cell therapies.

Mechanisms of Drug Resistance
Investigation of intrinsic and acquired resistance to targeted therapies and strategies to overcome therapeutic failure.

Drug Development and Advanced Delivery Systems
Development of novel targeted agents, nanomedicine, drug delivery platforms, and pharmacokinetic/pharmacodynamic studies.

Clinical Trials and Real-World Evidence
Phase I–IV clinical trials, observational studies, and real-world data evaluating efficacy, safety, and outcomes of targeted therapies.

Combination and Multimodal Therapies
Research on combined treatment strategies involving targeted agents, chemotherapy, radiotherapy, immunotherapy, and surgical interventions.

Supportive, Palliative, and Survivorship Care
Studies addressing symptom management, quality of life, supportive oncology, palliative care, and long-term survivorship in cancer patients.

Key Areas of Focus

Cancer Biology and Molecular Genetics

This area focuses on understanding the molecular and genetic mechanisms underlying cancer initiation, progression, metastasis, and resistance to therapy. It includes research on oncogenes, tumor suppressor genes, signaling pathways, genomic instability, epigenetic modifications, and molecular alterations that drive tumor behavior and therapeutic response.

Cancer Prevention and Risk Assessment

This section emphasizes strategies for cancer prevention through early risk identification, lifestyle modification, genetic screening, and population-based interventions. It covers studies on environmental, genetic, and behavioral risk factors, cancer epidemiology, chemoprevention, and predictive models for assessing individual and population cancer risk.

Diagnostic and Imaging Advances

Research in this area highlights innovations in cancer detection and diagnosis using advanced imaging technologies, molecular diagnostics, liquid biopsies, and artificial intelligence–assisted tools. The focus is on improving early detection, diagnostic accuracy, disease monitoring, and treatment response evaluation.

Targeted and Precision Treatment Modalities

This domain covers the development and clinical application of therapies designed to target specific molecular abnormalities in cancer cells. It includes targeted drugs, monoclonal antibodies, antibody–drug conjugates, and precision radiation techniques aimed at maximizing therapeutic efficacy while minimizing toxicity.

Personalized Medicine Approaches

This area addresses individualized cancer treatment strategies based on patient-specific molecular, genetic, and clinical characteristics. Research includes biomarker-driven therapy selection, pharmacogenomics, treatment stratification, and adaptive therapeutic approaches tailored to optimize patient outcomes.

Immunotherapy and Tumor Microenvironment

This section explores the interaction between cancer cells and the immune system, focusing on immune checkpoint inhibitors, cancer vaccines, adoptive cell therapies, and immune modulation strategies. It also examines the role of the tumor microenvironment in immune evasion, therapy resistance, and disease progression.

Translational and Clinical Oncology Research

This area promotes studies that bridge laboratory discoveries with clinical application, including preclinical models, early-phase clinical trials, and translational biomarkers. The goal is to accelerate the transfer of scientific innovations into effective clinical treatments for cancer patients.

Supportive and Palliative Oncology Care

This section focuses on improving quality of life for cancer patients through symptom management, pain control, psychosocial support, and palliative care interventions. It includes research on supportive therapies, survivorship care, end-of-life care, and patient-centered outcomes.

Global Cancer Burden and Future Directions

This area addresses the worldwide impact of cancer, including incidence, mortality, healthcare disparities, and access to treatment. It also explores emerging trends, future therapeutic strategies, health policy, and global initiatives aimed at reducing the cancer burden and improving outcomes across diverse populations.