Journal of Psychiatry and Mental Health

Hsien-Yuan Lane

PhD

  • Department: Psychiatry
  • University: China Medical University
  • Country: Taiwan

Professor Hsien-Yuan Lane is a Distinguished Professor at the College of Medicine, China Medical University (CMU), Taichung, Taiwan, where he serves as Director of the Graduate Institute of Biomedical Sciences and Director of the Department of Psychiatry. He earned his M.D. from Taipei Medical University in 1987 and completed his Ph.D. at the National Defense Medical Center, Taipei, in 2000. Over the course of his career, Dr. Lane has held significant leadership roles, including Director of the Graduate Institute of Clinical Medical Science at CMU, and Adjunct Research Fellow at the Institute of Biomedical Sciences, Academia Sinica. Professor Lane is internationally recognized for his research in neuropsychopharmacology, cognitive neuroscience, and precision medicine, with a focus on understanding genetic and non-genetic determinants of treatment response in mental disorders, and developing novel NMDA-enhancing agents for the treatment of psychiatric disorders and dementia.

  • Leadership Roles in Academia

    • Distinguished Professor & Director, Graduate Institute of Biomedical Sciences, College of Medicine, China Medical University (2016–present).

    • Distinguished Professor & Director, Graduate Institute of Clinical Medical Science, CMU (2009–present).

    • Director, Department of Psychiatry, College of Medicine, CMU (2007–present).

    • Adjunct Research Fellow, Institute of Biomedical Sciences, Academia Sinica (2006–2008).

  • Research Contributions

    • Pioneered studies on NMDA receptor–enhancing agents (e.g., sarcosine, sodium benzoate) for schizophrenia, depression, and dementia.

    • Advanced precision medicine in psychiatry through pharmacogenomics and biomarker discovery.

    • Published extensively in international journals across psychiatry, neuroscience, and pharmacology.

  • Awards & Honors

    • Y.Z. Hsu Scientific Paper Award – Biotechnology Category (2006).

    • CNS Drug Innovation Award, International College of Neuropsychopharmacology (2016).

    • Multiple National Innovation Awards, Taiwan (2013, 2017, 2019, 2021, 2022).

    • Outstanding Research & Technology Transfer Awards, Ministry of Science and Technology, Taiwan (2014, 2018, 2021, 2022).

    • Outstanding Alumni of Academic Achievement, Taipei Medical University (2023).

  • Professional Service & Community Engagement

    • Active member of international and national psychiatric and neuropharmacology associations.

    • Invited speaker at global conferences on psychiatry, neuroscience, and pharmacogenomics.

    • Mentor and supervisor for graduate students and young researchers in psychiatry and biomedical sciences.

  • Sodium benzoate treatment decreased amyloid beta peptides and improved cognitive function among patients with Alzheimer’s disease: secondary analysis of a randomized clinical trial
  • Sodium benzoate, a D-amino acid oxidase inhibitor, improved short-term memory in patients with mild cognitive impairment in a randomized, double-blind, placebo-controlled clinical trial
  • Symptomatic and cognitive effects of D-amino acid oxidase inhibitors in patients with schizophrenia: a meta-analysis of double-blind randomized controlled trials
  • Interpretable machine learning to evaluate relationships between DAO/DAOA (pLG72) protein data and features in clinical assessments, functional outcome, and cognitive function in schizophrenia patients
  • Increase in luteinizing hormone is linked to reduction in depression in patients with dementia: Secondary analysis of a randomized clinical trial of benzoate
  • IMPLICIT MEMORY AND EXPLICIT MEMORY PROFILES COMPARISONS BETWEEN PATIENTS WITH DIFFERENT MOOD DISORDERS
  • SEX- AND DOSE-DEPENDENT CATALASE INCREASE AND ITS CONTRIBUTION TO COGNITIVE IMPROVEMENT IN A BENZOATE DOSE- FINDING CLINICAL TRIAL FOR ALZHEIMER'S DISEASE
  • THE FUNCTIONAL CONNECTIVITY CHANGES OF THE RIGHT AMYGDALA ASSOCIATED WITH ANXIETY IN SCHIZOPHRENIA AND THE PRODROMAL PHASE
  • INTERACTIVE MODULATION OF NMDAR AND OXIDATIVE STRESS FOR THE TREATMENT OF MENTAL DISORDERS
  • The Mediating Role of Craving and Type D Personality between the Motivation To Online Gaming and Problematic Mobile Gaming Among Young Adults