MD
Dr. Lucienne Costa-Frossard França, MD, is a Consultant Neurologist at the National Multiple Sclerosis (MS) Reference Center of the Hospital Universitario Ramón y Cajal in Madrid, Spain, and a researcher at the Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS). She holds a Medical Degree (Licenciatura en Medicina y Cirugía) from the Universidad de Barbacena (Brazil, 1995), where she graduated with distinction (Premio José Bonifacio de Andrade), and completed her Specialization in Neurology at the Hospital Universitario Ramón y Cajal (Spain, 2006). Dr. Costa-Frossard is an established clinician-scientist with a dual profile in clinical neurology and translational neuroimmunology research, focusing on Multiple Sclerosis (MS). She has extensive experience in clinical trial coordination, having served as principal investigator and national coordinator for numerous multicenter trials in Spain on advanced MS treatments, including anti-CD20 therapies (ocrelizumab, ofatumumab, rituximab), S1P modulators, BTK inhibitors, extended-interval natalizumab, and CAR-T cell therapy approaches.
Clinical and Research Positions
Consultant Neurologist, National MS Reference Center, Hospital Universitario Ramón y Cajal (since 2009)
Researcher, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS)
Member, Red Española de Esclerosis Múltiple (REEM)
Advisor, Agencia Española de Medicamentos y Productos Sanitarios (AEMPS)
University Teaching and Coordination
Director & Coordinator, Master’s in Clinical Management of an MS Unit – Universidad Francisco de Vitoria
Coordinator, University Certificate in Differential Diagnosis in MS – Universidad Francisco de Vitoria
Professor, Master’s in Multiple Sclerosis – Universidad Francisco de Vitoria
Lecturer, Course in Neuroimmunology and MS – Universidad Autónoma de Madrid
Coordinator, Course on Demyelinating Diseases for Neurology Residents – Asociación Madrileña de Neurología
Editorial & Professional Engagements
Editorial Board Member, Iberoamerimed (Spain, Portugal, and Latin America)
Scientific Committee Member, MS-related national training and consensus programs
Research Projects and Collaborations
Participant in Spanish MS Network projects (REEM, RD17/0015/0001) and national I+D+i funded studies.
Co-author of over 60 peer-reviewed scientific papers in high-impact journals such as Frontiers in Immunology, Multiple Sclerosis Journal, and JAMA Neurology.
Publications and Books
Author and co-author of several MS-focused medical texts, including:
Gestión Clínica en Unidades de Esclerosis Múltiple (3 volumes)
Importancia de la Vitamina D en los pacientes con Esclerosis Múltiple
Planificación Familiar y Esclerosis Múltiple: 100 respuestas clave
Libro Blanco de la Esclerosis Múltiple en España (2020)
