PhD
Dr. Mahmoud Kamal Mohamed Ismaeil Singer is a distinguished biomedical scientist specializing in cancer immunotherapy, molecular immunology, and translational oncology research. He currently serves as a Postdoctoral Scientist at the School of Medicine, University of California, Irvine (UCI), USA, where he will assume the role of Assistant Project Scientist beginning in October 2025. Dr. Singer earned his Ph.D. in Biochemistry (with a minor in Immunology) from the Faculty of Science, Ain Shams University, Cairo, Egypt, following his Master’s and Bachelor’s degrees in Biochemistry from the same institution. His doctoral research focused on developing innovative immunotherapeutic approaches for hepatocellular carcinoma, integrating cellular immunology with biochemical and molecular biology techniques. Over the course of his career, Dr. Singer has combined academic research, clinical collaboration, and industry experience. He has worked extensively in preclinical and clinical research, contributing to projects on hepatocellular carcinoma, multiple myeloma, leukemia, and other malignancies. His work at UCI focuses on novel combination immunotherapies, tumor microenvironment modulation, and T-cell receptor signature identification in cancer.
1. Research and Academic Roles
Assistant Project Scientist (starting Oct 2025) and Postdoctoral Scientist (2022–2025) at the School of Medicine, University of California, Irvine (UCI) – leading preclinical and clinical research in cancer immunotherapy and translational oncology.
Former Postdoctoral Fellow at City of Hope National Medical Center, USA – investigated immune mechanisms of disease progression and therapeutic response in multiple myeloma.
Former Lecturer and Researcher at the National Cancer Institute, Cairo University – taught Immunology and Cancer Cell Biology and conducted research on leukemia and liver cancer immunology.
2. Editorial and Peer Review Contributions
Reviewer Editor, Springer Nature (appointed October 2025).
Editorial Board Member, European Journal of Preventive Medicine (2024–2027).
Guest Editor, Journal of Visualized Experiments (JoVE) – Special Issue: Cancer Immunotherapy and Infectious Diseases Vaccines.
Top 1% Global Reviewer (Publons/Clarivate, >366 peer reviews as of September 2025).
Active peer reviewer for more than 60 international journals, including Cancers, Cells, Frontiers in Immunology, Cancer Cell International, OncoImmunology, Leukemia Research, Viruses, Vaccines, and Journal for ImmunoTherapy of Cancer.
3. Publications and Scientific Output
Authored and co-authored over 35 peer-reviewed publications in oncology, immunology, and translational medicine journals such as Blood, Cancers, Cells, Frontiers in Immunology, J Hematol Oncol, and Microorganisms.
Contributed book chapters published by Springer Nature on topics including metabolic communication in the tumor microenvironment and host–microbe interactions in cancer and infection.
Presented scientific abstracts and posters at leading international conferences, including the Society for Immunotherapy of Cancer (SITC) 40th Annual Meeting (2025).
4. Innovation and Patents
Inventor of the U.S. Patent Application No. 63/600,892 (2023) titled “Dynamical System Modeling for Immune Stability Analysis.”
Actively involved in developing novel immunotherapeutic concepts for solid tumors submitted to NIH (R01/R21), DOD, and CIRM grant programs.
5. Professional Memberships
Member of the American Association of Immunologists (AAI)
Member of the American Association for Cancer Research (AACR)
Member of the Society for Immunotherapy of Cancer (SITC)
Member of the American Society of Clinical Oncology (ASCO)
Member of the Multiple Myeloma Research Foundation (MMRF)
6. Teaching and Mentorship
Experienced lecturer in Immunology, Biochemistry, and Cancer Cell Biology for graduate students.
Mentor for young researchers in flow cytometry, molecular techniques, and animal model development.
