Journal of Targeted Oncology Research

Dr Zahra Shahbazi

PhD

  • Department: Gastroenterology and Liver Diseases
  • University: Shahid Beheshti University of Medical Sciences
  • Country: Iran

Dr. Zahra Shahbazi is a molecular geneticist and researcher specializing in medical genetics, cancer susceptibility, and next-generation sequencing based diagnostics. She earned her Ph.D. in Medical Genetics from the Pasteur Institute of Iran, where her doctoral research focused on the evaluation and characterization of genetic mutations in severe combined immunodeficiency patients using advanced sequencing methods. She also holds an M.Sc. in Molecular Genetics from Shahid Chamran University of Ahvaz and a B.Sc. in Animal Biology from Razi University of Kermanshah. Dr. Shahbazi currently serves as a Principal Investigator at the Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center, part of the Research Institute for Gastroenterology and Liver Diseases at Shahid Beheshti University of Medical Sciences in Tehran, Iran. She has also directed the Genetics Laboratory at Faraby Pathobiology and Genetic Laboratory, where she managed genetic testing programs covering cancer mutations, carrier detection, and prenatal diagnosis.

  1. Principal Investigator (PI) at the Basic and Molecular Epidemiology of Gastrointestinal Disorders Research Center,

    Research Institute for Gastroenterology and Liver Diseases,
    Shahid Beheshti University of Medical Sciences, Tehran, Iran (since Oct 2024).

  2. Director of Genetics Laboratory, Faraby Pathobiology and Genetic Laboratory, Hamedan, Iran (2020–2024).

    • Supervised advanced genetic tests including WES analysis, cancer mutation detection, and prenatal diagnostics.

  3. Teaching Activities:

    • Lecturer in Immunogenetics at Alborz University of Tehran.

    • Instructor in Genetics, Bioinformatics, and Biology Laboratory at Payame Noor University, Semirom Unit.

  4. Congress & Workshops:

    • Participant and presenter at multiple national and international congresses, including the 1st International Biomedical Congress of Iran and 12th Iranian Genetic Congress.

    • Executive reviewer and committee member for the International Congress of Laboratory and Clinic.

    • Workshop participation in R software, SiRNA design, NGS variant interpretation, flow cytometry, and bioinformatics.

  • Mutations in COL6A Gene Family Responsible for Muscular Dystrophies in Three Unrelated Families.
  • Homozygosity for Robertsonian Translocation (14q;15q) in a Newborn with a Familial History of Recurrent Abortion and Newborns Affected by Hepatosplenomegaly: A Case Report.
  • A de novo TINF2, R282C Mutation in a Case of Dyskeratosis Congenita Founded by Next-Generation Sequencing.
  • Hb Narges Lab: A Novel Hemoglobin Variant of the β-Globin Gene.
  • New Heritable ATRX Mutation Identified by Whole Exome Sequencing and Review.
  • Prevalence of JAK2 V617F Mutation in Iranian Patients with Myeloproliferative Neoplasms.
  • Distribution of Disease-Causing Mutations Through Different Protein Domains in Patients with Severe Combined Immunodeficiency.
  • Genetic Mutations and Immunological Features of Severe Combined Immunodeficiency Patients in Iran.
  • pH-Responsive Mesoporous Silica Nanoparticles Functionalized with Folic Acid and Chitosan for Targeted Epirubicin Delivery: In Vitro and In Vivo Efficacy in Breast Cancer.